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Finally, the increase in the mitochondrial respiratory capacity and the reduction in ROS production would aid GSCs to adapt to stress, thereby resisting cell death (Park et al., 2019)

SLC7A11 functions in a variety of roles in cancer including metabolic reprogramming, nutrient dependency, growth, proliferation, invasion, and drug resistance ( Figure 1 )

Acta Pharmacol Sin 23:412422 Sikiric P, Seiwerth S, Brcic L et al (2006) Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)