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Still, these data broadly indicate a robust persistence of mitochondrial respiration under cystine deprivation that occurs independent of an expected insult to the IMM 15,22

Cytoplasmic ferritin sequesters iron into a biochemically inert form as a result of the ferroxidase activity of the H subunit [35], with each ferritin complex storing up to 4500 iron atoms as ferric ions (Fe) [36]

Upadhaya S, Neftelinov ST, Hodge J, Campbell J (2022) Challenges and opportunities in the PD1/PDL1 inhibitor clinical trial landscape

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