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After adding standards or samples and a biotin-conjugated GABA antibody, avidin-HRP was added and incubated

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In an MPTP-induced Parkinson's disease animal model, intracerebroventricular injection of PBzyme decreases dopaminergic degradation and inhibits neuroinflammation by downregulating the activation of microglial nucleotide-binding domain and leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasomes and caspase-1 by scavenging reactive oxygen species which ultimately leads to microglia pyroptosis (Ma et al., 2022)

On dermoscopy, after 3 months of treatment, some improvement was noted on right side in the form of decreased shades of pigmentary network in cases of epidermal melasma and decreased irregularity of pigmentary network, decreased number of granules and globules in cases of mixed melasma in comparison with baseline