DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE cyclopropene Product Name Phthalimidinoglutarimide-propargyl-PEG4-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG4-OH

Product Name Phthalimidinoglutarimide-propargyl-PEG4-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG4-OH CAS Number n/a Related CAS Molecular Formula C24H30N2O8 Molecular Weight 474

Product Name Lenalidomide-5'-CO-C3-acid Synonyms CAS Number 2759015-47-7 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373

95 SMILES Cl

Product Name Pomalidomide Synonyms Pomalidomide CAS Number 19171-19-8 Related CAS Molecular Formula C13H11N3O4 Molecular Weight 273

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE cyclopropene Product Name Phthalimidinoglutarimide-propargyl-PEG4-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG4-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further