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To this end, several ubiquitin ligases have been harnessed for targeted protein degradation (TPD), yet structural data on their ternary complexes remain scarce, limiting insight into the molecular basis of these interactions

Es importante situar estos hallazgos correctamente: todos los datos aqui resumidos proceden de estudios preclinicos y exploratorios

These reprogramming factors can reset the cellular state, erasing the specialized characteristics of the somatic cells and reverting them back to a pluripotent state [74]