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But it has not been demonstrated that such animal use has been essential or even reliable for medical advancement. Defenders of animal testing often argue that while it may be imperfect, it is our only option for advancing human medicine

Lung cancer is the leading cause of years of life lost from cancer (2,365,000 years of life lost), but colorectal cancer is the second (804,000 years of life lost), and female breast cancer the third (778,000 years of life lost) [50]

The reduced blood flow also makes the area more prone to infection after procedures