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One of the better characterized metabolic phenotypes present in tumor cells is the Warburg effect, which gives preference to ATP generation through glycolysis, even under normal oxygen concentrations, over ATP synthesis through the electron transport chain in the mitochondria (Warburg, 1956

Because the internet is often full of misleading or biased information, I would like to provide at least some basic information here

[] There are five bias domains: (1) bias due to the randomisation process, (2) deviation from intended intervention, (3) missing outcome data, (4) measurement of outcomes, (5) selection of the reported result, and overall risk of bias judgment