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It completely blocks absorption, with no folate being able to be transported

"Cardio- and Cerebrovascular Events in HIV-Infected Persons." AIDS 18.13 (2004): 1811-7

or wherein the presence or increase in copy number, amount, and/or activity of at least one target listed in table 1 and/or the absence or decrease in copy number, amount, and/or activity of at least one target listed in table 2 in monocytes and/or macrophages from subsequent samples as compared to the copy number, amount, and/or activity of monocytes and/or macrophages from the first sample indicates that the monocytes and/or macrophages of the subject have a down-regulated inflammatory phenotype

Uniform Affinity-Tuning of N-Methyl-Aminoacyl-TRNAs to EF-Tu Enhances Their Multiple Incorporation