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10.1007/s10059-013-0192-9 Mol

A locus control region consisting of two DNase-I hypersensitive regions (HS), specifically HG-I site, 14.5 and 30 kb upstream of GH1 appears to be required for pituitary-specific GH1 expression (293)

Mg 2+ supports this adaptability by regulating the activity of cytoskeletal proteins, helping to preserve structural integrity and functional plasticity under hypoxic stress (Vakhrusheva et al., 2022)