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The ability of gut microbiota to communicate with the brain and in turn induce behavioral changes is emerging as an interesting concept in autism

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This animal study was performed in accordance with the following: - UK guidance on the operation of the Animals (Scientific Procedures) Act of 1986 and associated guidelines - EU Directive 2010/63 for the protection of animals used for scientific purposes - The NIH (National Research Council) Guide for the Care and Use of Laboratory Animals The study also complies with the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines

Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma