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In the prenatal period, the entire meniscus is vascularized and becomes more and more localized as the knee matures

Pulmonary hypertension is associated with the development of cor pulmonale, defined as hypertrophy of the right ventricle resulting from diseases affecting the function and/or structure of the lungs, except when these pulmonary alterations are the result of diseases that primarily affect the left side of the heart, as in congenital heart disease. This is a pathological definition and the clinical diagnosis and assessment of right ventricular hypertrophy is difficult in life