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Description

LX7101 has undergone both Phase 1 and 2 trials for POAG and OHT starting in 2012, while ATS907 was assessed in Phase 1 and 2a trials in the same year (36)

The incidence of spontaneous amyloidosis usually increases with age and is common in CD-1 mice (Harada et al

In the presence of SF-1-dependent ArPII promoter, SF-1 activation led to the induction of CYP19A1 expression and subsequent activity ( 3 ( Figure 2A right part)