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Description

Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

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T1AM/TAAR1 system reduces inflammatory response and -amyloid toxicity in human microglial HMC3 cell line

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Consequently, ferroptosis inhibitors have shown significant therapeutic potential in treating these conditions

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In this case, supporting small and sustainable changes to lifestyle can still yield important improvements, but additional therapeutics are often still necessary to address the detrimental chronic presence of NAFLD

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