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Lancet (2016) 387:15667.10.1016/S0140-6736(15)00465-1 36 Petnicki-OcwiejaTHrncirTLiuYJBiswasAHudcovicTTlaskalova-HogenovaHet alNod2 is required for the regulation of commensal microbiota in the intestine