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Besides the induction of inflammatory macrophages, nicotine treatments promote the M2 polarization, reduces the secretion of several proinflammatory cytokines in macrophages, and suppresses the alveolar macrophages to present the inhaled antigen to lymphocytes [130, 131]

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Pritzkers spending plan for the budget year that begins July 1 includes $65 million in new revenue from proposals to increase the $1.98-per-pack cigarette tax by 32 cents and apply the states wholesale tobacco tax to e-cigarettes