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Disorders of homocysteine metabolism

AD is characterized by a progressive reduction in the num ber and maturation of adult neurons in the dentate gyrus (DG) of the hippocampus (Moreno-Jimenez et al., 2019), suggesting an impairment in hippocampal neurogenesis that is closely correlated with the loss of hippocampal functions and cognitive decline (Hollands et al., 2017

Singhal RK, Anderson ME, Meister A (1987) Glutathione, a first line of defense against cadmium toxicity

Mi et al., 2009) has led to the emergence of a growing number of open-source computational modelling tools such as Cell Designer (Funahashi et al., 2008), which allows users to easily draw and kinetically model biochemical pathways (Le Novre et al., 2006), and provides an interface to many other metabolic pathway enrichment databases (Xia et al., 2010)