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Description

Astrocytes, which are specialized glial cells in the brain, actively absorb excess glutamate (a highly excitatory neurotransmitter that can cause severe nerve damage and excitotoxicity if left unchecked in the synaptic cleft) and safely convert it into inert, harmless glutamine

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doi: 10.1038/msb.2010.46 141 AmetajBNZebeliQIqbalS

Effects and relationship of ERK1 and ERK2 in interleukin-1-induced alterations in MMP3, MMP13, type II collagen and aggrecan expression in human chondrocytes