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propagating the population of host cells for multiple generations

When energy is abundant, citrate is exported from mitochondria through the mitochondrial citrate carrier and cleaved by ATP citrate lyase to generate acetyl-CoA, which is then converted by acetyl-CoA carboxylase into malonyl-CoA, the first committed intermediate in fatty acid biosynthesis ( Once inside the cell, FFAs are bound by fatty acid-binding proteins (FABPs), which facilitate their distribution to distinct intracellular compartments and metabolic pathways ( These early steps in fatty acid handling have important consequences for macrophage function

Abstraction of the hydrogen atom at C14 generates phytoprostanes G 1 (PPG 1 ) of type I, while hydrogen abstraction at C-11 yields PPG 1 of type II