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Our finding that several diseases show lowered blood NAD + levels and overall imbalanced redox metabolites is intriguing, as it suggests that a variety of disease processes increase NAD + usage, potentially by activated repair processes including PARP enzymes a major user of NAD +8 .The results have high potential relevance for clinical and research applications, follow-up of metabolic interventions and detection of disease-induced NAD + or glutathione deficiency to select patients for treatment

Goodson JM

Read more here: To view or add a comment, sign in Day 5 Understanding Intestinal Models in Drug Absorption Before diving into some advanced in vitro intestinal models tomorrow, I wanted to share a quick overview of how drug absorption across the intestinal barrier is studied

The RSM establishes water as the foundational tier of the resource hierarchy, reflecting both its abundance in wastewater and its critical role in human well-being