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How to effectively restrain tumor immune tolerance still requires long-term investigation

3.5 Anticancer mechanisms of isothiocyanates 3.5.1 Induction of apoptosis and cell cycle arrest Isothiocyanates (ITCs) are bioactive compounds derived from glucosinolate precursors abundant in cruciferous vegetables (e.g., broccoli and watercress) (106)

10.1093/humrep/dem408 74 HaraguchiH.HirotaY.Saito-FujitaT.TanakaT.Shimizu-HirotaR.HaradaM.et al (2019)

IGFBPs and IGFBP Proteases Like the above attempts to pinpoint the role of important ligands and receptors in the axis, steps to assess the role of IGF binding proteins involved in modulating IGF-I and IGF-II bioactivity were taken (reviewed by Pintar (25))