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Co-culture of human gastric mucosal epithelial cells with NPs results in decreased proliferation and increased apoptosis (46)

Overall, these works suggest that low pH induces the production of glutathione and succinoglycan which are both involved in stress tolerance and symbiosis

With the observation of the above docking results with the drug and carriers, it may be suggested that the hydroxyl group may serve as a prerequisite to induce inhibition at the binding pockets of the iNOS oxygenase receptor