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The strategy includes: Medical evaluation (iron panel, celiac screening, blood loss sources) Strict gluten-free diet under guidance Iron supplementation or dietary increase iron rich foods

Overexpression of vascular endothelial growth factor is responsible for the hematogenous recurrence of early-stage gastric carcinoma

Drugs targeting rare diseases with limited generic development incentive often rely more on ODE than on Orange Book patents because the patient population is too small to attract a Paragraph IV filer willing to absorb litigation costs

Some individuals may benefit from combining both approaches under medical supervision