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5 System biology comprises various biological networks like genetic regulatory, protein interaction, metabolic, and signaling networks

Munir R, Lisec J, Swinnen JV, Zaidi N

The natural compound, neoalbaconol, targets the ubiquitin system in EBV-related cancer The ubiquitin-proteasome system (UPS) is emerging as a novel target for anticancer drugs and molecular diagnostics

They also seem to be involved in the clearance of the CSF (or ISF) from the glymphatic system 2, 17 , and also in the regulation of the ICP (through a direct reabsorption of the CSF from the subarachnoid space) 5