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Iain Gately, the author of the 2007 book Tobacco: A Cultural History of How an Exotic Plant Seduced Civilization, writes, The concept of warning labels in the air since 1957, when a bill had been introduced in the Senate requiring all cigarette packs to carry the label, Warning: Prolonged use of this product may result in cancer, in lung, heart and circulatory ailments and in other diseases. He adds, This bill was killed by tobacco industry supporters presumably on the grounds of aesthetics

Beginning in the 1750s, Quakers support for slavery and the products of slave labor started to erode, as reformers like Quaker John Woolman urged their co-religionists in the North American Colonies and England to bring about change