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Another small, randomized, double-blind trial in 93 individuals with low vitamin D status found no additional benefit of B-vitamin supplementation (50 mg/day of vitamin B6, 0.5 mg/day of folic acid, and 0.5 mg/day of vitamin B 12 ) on markers of bone health over a one-year period beyond that associated with vitamin D and calcium supplementation

This type of reaction is often seen in response to allergens such as insect bites and certain medications and can cause symptoms such as joint pain, skin rashes, and eye inflammation

Venn BJ 1 , Green TJ, Moser R, McKenzie JE, Skeaff CM, Mann J

Without enough, you might feel tired, weak, and have nerve problems