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Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical transcription factor that governs the body's endogenous antioxidant defense system

10.1038/mp.2017.171 176 van DuijnS.BulkM.van DuinenS

Higher doses of TM elicited UPR activation in ET-treated cells to an extent comparable to that observed with lower doses in non-ET-treated cells (Figure 2C)