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A recent systematic review and meta-analysis of vitamin D therapy in patients with IBD and vitamin D deficiency has shown that this supplementation is effective not only for the correction of vitamin D levels but also for improving scores of clinical disease activity and biochemical markers (361)

Of course, like any novel technology, the research generally lacks the ideal sample size and design

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Glutathione is synthesized in a two-step process, in which the first and rate-limiting enzyme -glutamylcysteine synthetase (ECS or GSH1) converts glutamate and cysteine to EC, then glutathione synthetase (GSH2) forms glutathione by the ligation of an additional glycine to the intermediate 42,43 (Fig