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Metabolic signaling and longevity-related research

It is a quinolinium salt substituted at position 5 with an amino group and at position 1 with a methyl group

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To focus on oxidative stress as a main damaging factor in an in vitro model is reasonable, as the diverse upstream causes for PN (hyperglycemia, dyslipidemia, some chemotherapeutics, alcohol abuse) converge into one prominent metabolic disturbance: the production of ROS and, thus, increased oxidative stress