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Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

10.1016/j.jchromb.2019.121854 472

NAC protected against oxidative stress through acting on this newly disclosed Nrf2/GR/GSH pathway, by which NAC elevated the biosynthesis of protective GSH to repair and reconstitute the defense system destroyed by phosgene