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Synergistic Mechanisms of Action The rationale for combining Methylene Blue and Dihexa is based on complementarity

Pregnancy and weight: Being pregnant, being overweight or obese can increase the risk of muscle spasms

In case of poor results with methylfolate, either mega doses of methlfolate should be given (up to 15 mg were used in studies) to provide sufficient methyl groups or SAM can be given directly

Iqbal N, Masood A, Nazar R, Syeed S, Khan NA (2010) Photosynthesis, growth and antioxidant metabolism in mustard (Brassica juncea L.) cultivars differing in cadmium tolerance