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(4) Outcomes: anxiety or depressive-like behavior and neuroinflammation

Symptoms of B12 deficiency may include Megaloblastic anemia (large red blood cells with abnormal nuclei) Fatigue Paleness Heart palpitations Dementia Weight loss Infertility Numbness and tingling in hands and feet Depression, mania, delirium, psychosis Poor pregnancy and breastfeeding outcomes (neural tube defects, developmental delays, failure to thrive, anemia in offspring) Low red and white blood cell counts or platelets Glossitis of the tongue Erectile dysfunction or bowel/urinary incontinence Recommended Daily Intake for B12 Recommended Dietary Allowance (RDA) Daily B12 requirements depend on age, sex, and dietary intake (5) Assessing B12 Status Typically serum B12 levels are used to determine vitamin B12 deficiency (keep in mind normal value ranges may vary slightly depending on the laboratory)

The portion of the FITC spectrum detected in the PE detector, and the PE spectrum detected in the APC detector must be subtracted from the PE and APC signals using compensation

Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial