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Description

SP can target the macrophages to accelerate the protein degradation of Kelch-like ECH-associated protein 1 (KEAP1) via microtubule-associated protein 1 light chain 3 (LC3)-mediated autophagy and ubiquitin-mediated proteasome degradation

6.Townsend, D

After absorption, iron ions are oxidized by ceruloplasmin in the blood to trivalent iron ions, which then bind to transferrin receptor and enter the cells in the form of pinocytosis for hematopoietic cells

Psychological factors, including a high frequency of stressful life events and preceding vitiligo onset, are associated with the development of vitiligo