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In der Praxis ist das einzige konsistent berichtete Nebenwirkungssignal: Schmerzen an der Injektionsstelle bei wssriger Lsung

These findings highlight the potential of metabolic interventions to restore immune homeostasis through Treg modulation

Upon ischemic injury in stroke, neuronal HMGB1 is abundantly released into the extracellular space, both by active secretion and passive release, to accumulate in the ischemic core of the acute phase and to activate resident brain immune cells, leading to the recruitment of mononuclear cells that further amplify inflammation (Singh et al., 2016)