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Jungas, R

MEK blockade converts AML differentiating response to retinoic acid (RA) into extensive apoptosis: Involvement of Bcl-2 modulation and ROS accumulation

Protein oxidation can result in amino acid modifications (oxidative protein modification), accumulation of cross-linked reaction products, peptide chain fragmentation, and augmented electrical charges (Parthasarathy et al., 1999