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The oxidative stress is the result of the imbalance of the antioxidant system in favor of prooxidants, which interferes with the GSH/GSSG system in the antioxidant defense and the regulation of gene expression, the synthesis of DNA and proteins, cell proliferation and apoptosis, and cytokine production and protein glutathionylation, due to alteration of certain cellular functions

Discontinuation of the offending statin is important for both preventing progression of liver injury as well as monitoring subsequent hepatic injury evolution

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The wipe helps remove ostomy adhesive and other bodily fluids from the skin barrier to give the new bag or pouch a better connection to the skin, forming a better seal for optimal use