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These structural modifications significantly reduce IGF-1s binding affinity to IGF-binding proteins (IGFBPs), increasing the availability of the active peptide during in-vitro experimentation

Physiol Res 70(Suppl 4):S683 Rauscher FM, Sanders RA, Watkins JB 3rd (2001) Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats