Indeed, upregulation of pathways involved in inflammation, bioenergetics and lipid processing have been reported in arrays of sciatic nerves from preclinical models of T1DM and T2DM 52,53
14 This heightened sensitivity has been observed in various contexts, including the enhancement of gemcitabine efficacy in mice with prostate cancer xenografts and the increased efficacy of chemotherapy in triple-negative breast cancer via the upregulation of ROS
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Like Vitamin C, it inhibits tyrosinase