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Description

Results NRF2 activation in NSCLC cells increases system x c activity and [ 18 F]FSPG cell retention SLC7A11 is a NRF2-regulated gene which encodes the glutamate/cystine antiporter xCT, a key component of system x c

Rgnration dautres antioxydants : Le Glutathion contribue la rgnration de la vitamine C et de la vitamine E partir de leurs formes oxydes, amplifiant ainsi le rseau antioxydant global au sein de la cellule

doi: 10.1097/MCO.0000000000000335

QVTLKESGPALVKPTETLTLTCTLSGFSLNNARMAVSWIRQPPGKCLEWLAHI FSNDEKSYSTSLKSRLTISKDTSKGQVVLTMTNMDPVDTATYYCARIVGYGSG WYGYFDYWGQGTLVTVSSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVG DRVTITCRASQDIRNDLGWYQQKPGKAPKRLIYAASTLQSGVPSRFSGSGSGT FL_3_CCxCD Bispecific EFTLTISSLQPEDFATYYCLQHNSYPLTFGCGTKVEIKSGGGGSEVQLVESGGG 3-scFc molecule LVQPGGSLKLSCAASGFTFNKYAMNWVRQAPGKGLEWVARIRSKYNNYATY YADSVKDRFTISRDDSKNTAYLQMNNLKTEDTAVYYCVRHGNFGNSYISYWA YWGQGTLVTVSSGGGGSGGGGSGGGGSQTVVTQEPSLTVSPGGTVTLTCG SSTGAVTSGNYPNWVQQKPGQAPRGLIGGTKFLAPGTPARFSGSLLGGKAA LTLSGVQPEDEAEYYCVLWYSNRWVFGGGTKLTVLG 361