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doi: 10.1016/j.foodchem.2016.05.074 139 PujiastutiD

Disulfiram: DSF is a dithiocarbamate compound that treats alcohol dependence by targeting aldehyde dehydrogenase (ALDH), while acid condition reduces DSF to diethyldithiocarbamate (DTC) and invests the capacity to combine Cu(II) (Viola-Rhenals et al., 2018)

In contrast, the diabetes mice resulted in only 0.08 0.03 and 0.15 0.02 nmol/mL following administration of a low and high dose sinigrin in Figure 5A

A protocol planned interim analysis was conducted for this cross-over study when 12 participants completed the first administration period (period 1), in order to re-assess the sample size based on the primary outcome data