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was largely based on data from two identical Phase 3 clinical trials, ASCLEPIOS I (NCT02792218) and ASCLEPIOS II (NCT02792231), that collectively enrolled more than 1,800 patients with RRMS or active SPMS at nearly 400 sites worldwide

116 The role of Cu in the pathogenesis of ALS is unclear and currently under study

The loss of vascular Cxcr4 expression likely disrupts the crucial SDF-1/CXCR4 signaling axis that anchors HSCs to the niche, a cornerstone of hematopoietic regulation 55

Despite the definition of human trafficking provided by the TVPA, proper identification of victims remains one of the greatest challenges