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Factors that commonly contribute include: A sudden increase in training volume or intensity Frequent jumping or repetitive running Tight quadriceps or hamstring muscles Weak gluteal muscles that reduce lower limb stability Limited movement in the hips or ankles Poor landing or squatting mechanics Not allowing enough recovery between workouts Worn or unsuitable footwear during physical activity Patellar tendonitis rarely develops because of a single movement

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Pernicious anemia is associated with an increased incidence of carcinoma of the stomach, but this is believed to be related to the underlying pathology and not to treatment with vitamin B 12