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Activated caspase-1 promotes inflammation by cleaving pro-interleukin-1 (pro-IL-1) and pro-IL-18 into their mature and biologically active forms [31]

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Acknowledgements This study was supported by the Bavarian Cancer Research Center (BZKF) (TANGO to S.K.), the Deutsche Forschungsgemeinschaft (DFG, KO5055/3-1 to S.K.), Marie Sklodowska-Curie Training Network for Optimizing Adoptive T Cell Therapy of Cancer (funded by the Horizon 2020 programme of the European Union

Conditions impacting the pancreas like celiac disease, cystic fibrosis, chronic pancreatitis, and/or pancreatic cancer all potentially reduce the pancreas ability to manufacture and release digestive enzymes

Discussion Myeloid mimicry induced by IFN signaling was recently described as a mechanism of immune evasion in mouse models of glioblastoma multiforme 41