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Our observations are consistent with a previous clinical study in solid tumors where continuous infusion of BSO depleted tumor GSH below 10% of pretreatment levels with minimal systemic toxic effects

Protects Against Premature Aging Glutathione is a powerful antioxidant that helps fight free radicals, reducing signs of aging such as fine lines, wrinkles, and dullness

For transfection, each well was treated with a complex formed by combining 2.0 g of the pHaloTag-PS plasmid (purchased from Beijing Solarbio Science & Technology Co., Ltd.) with 6 L of Lipofectamine 3000 transfection reagent in 100 L of Opti-MEM I reduced serum medium, according to the manufacturers protocol

To identify potential outliers, principal component analysis was performed after log transformation and Pareto scaling were applied to the entire dataset using MetaboAnalyst 5.0 online software ( Two control samples were identified as outliers and removed from the dataset before further statistical analyses were performed