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Consistent with previous findings, the inhibitory effect of combination treatment on cell viability was partially eliminated by the overexpression of -catenin and phospho--catenin Ser552 , indicating that downregulation of -catenin signaling contributed to the synergistic antitumor activity of NFX and OXA (Fig

However, more recent evidence in mice suggests that intracellular adenosine mediates sleep homeostasis through glial-neural circuits

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