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In the nucleus, GSTP bound to HMGB1 and consequently prevented HMGB1 to translocate to the cytoplasm and release from macrophages

From polydeoxyribonucleotides (PDRNs) to polynucleotides (PNs): Bridging the gap between scientific definitions, molecular insights, and clinical applications of multifunctional biomolecules

Rather than finding a single best antioxidant target to support the regulation of age-related decline in redox state, we explore an activator of the cells balanced antioxidant/oxidative redox response, the transcription factor Nrf2 (nuclear erythroid factor-like 2)

In an independent LAPC9-AI therapeutic study (Fig