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The Mannheim process produces sodium sulfate by reaction of sodium chloride and sulfuric acid

Consistent with this, the observation of reduced viability of H9c2 cardiomyoblasts and HUVEC endothelial cells to values below 80% when incubated with GSNO concentrations above 75 m and 156 m, respectively, indicates that the cytotoxic effect of high GSNO concentrations, such as 500 m, may prevail over the beneficial effect of cardioprotection in I/R