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2019, Abbasi et al

While an overdose of APAP yields peak serum concentrations (10 20 g/mL) within 4 hours, a patient taking the medication safely will achieve peak concentrations within 1.5 hours, with a half-life of 1.5 3 hours

To promote their growth, tumor cells require significant nutrition to generate metabolites that contribute to modifying the tumor microenvironment (TME) [5, 6]