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suggested that an organized process of senescence in, and ultimately removal of, a subgroup of endometrial stromal cells contributes to the overall remodeling and regrowth of the endometrium during the proliferative phase ( Cellular senescence is a phenomenon described in proliferative tissue including the endometrium and can occur under physiologic conditions when a cell reaches its final telomere length or under the influence of oxidative stress and other stressors such as DNA damage, inflammation, and epigenetic modifications ( While serving a physiologic function, senescence may also be associated with pathological conditions such as neurodegeneration and atherosclerosis, cancer and immune system dysregulation

In this chapter, by G6PD deficient, we mean Gd males and Gd / Gd females