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It has also regulated tryptophanserotonin metabolism, modulated the HPA axis and shifted inflammatory markers (reduced IL-6, IFN- and increased IL-10), supporting the effect of probiotic on reducing anxiety-like behavior via MGBA regulation (Jia et al., 2024)

Hypothesized treatment for migraines using low doses of tryptophan, niacin, calcium, caffeine, and acetylsalicylic acid

Because it is so versatile, it is often considered a "conditionally essential" amino acid, meaning that while you usually make enough, there are many real-world scenarios where you might need an extra boost from your diet or a high-quality supplement

Science 296 , 490494 (2002)