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Glutathione plays important roles in antioxidant defense, nutrient metabolism, and regulation of cellular events including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production and immune response 67

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While a constant exposure of quinone is not necessarily representative of an in vivo scenario, it is however, much more representative of an in vitro situation, whereby a constant source of quinone is essentially available in the extracellular media during cell culture 27

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